Tirzepatide with B12
Dual-action GLP-1/GIP therapy — appetite control, insulin sensitivity, and body composition. Standard injection.
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GLP-1 Weight Loss
GLP-1 medications — semaglutide and tirzepatide — are among the most rigorously studied weight-loss therapies in modern medicine. Thesis Health makes them accessible — physician-supervised and compounded by licensed US pharmacies through our clinical partner, Altro Health, at a fraction of brand-name pricing. The same active ingredients as Ozempic® and Mounjaro®* — now including needle-free sublingual options.
Free Field Guide
GLP-1s are one powerful tool — but they work best as part of the bigger picture. Our free field guide breaks down the peptides and hormones we work with, including the newly compoundable options, in plain language.
Get the free guideGLP-1 Plans
Tirzepatide and semaglutide — as a standard injection or a needle-free sublingual. Pick microdose or full dose on any plan.
A fraction of name-brand — same active ingredient.
Brand-name GLP-1s can run well over $1,000 a month. Thesis starts at $199/mo — roughly $7 a day, about the cost of a coffee — for the same active ingredients* as Ozempic® and Mounjaro®.
*Compounded medications contain the same active ingredient as the brand-name drug but are not FDA-approved finished products. Prescribed and dispensed through our clinical partner, Altro Health.
Standard injection
Needle-free · under the tongue
Standard injection
Needle-free · under the tongue
Physician evaluation required. *Compounded medications contain the same active ingredient but are not FDA-approved finished drug products. HSA/FSA eligibility varies by plan. Not available in all states. Individual results vary.
The Clinical Evidence
GLP-1 medications aren't hype — they're among the most rigorously studied weight-loss therapies in modern medicine. Two landmark, peer-reviewed trials set the benchmark:
Semaglutide — the STEP 1 trial
Adults lost an average of ~15% of their body weight over 68 weeks. New England Journal of Medicine, 2021
Tirzepatide — the SURMOUNT-1 trial
At the highest dose, the average was ~21% of body weight over 72 weeks — the most of any GLP-1 to date. New England Journal of Medicine, 2022
See Your Potential
Slide to your weight today
Projected from the average results of the STEP 1 and SURMOUNT-1 trials. Individual results vary — this is an illustration, not a guarantee or medical advice.
New to GLP-1s?
Our free GLP-1 course covers how these medications actually work, protecting your lean mass, and keeping the results. No cost, no catch.
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All Formulations
Injection or sublingual, microdose or full dose — filter to the option that fits you.
Dual-action GLP-1/GIP therapy — appetite control, insulin sensitivity, and body composition. Standard injection.
Get started Lower-dose dual-action therapy — gradual, tolerable progress with minimal side effects.
Get started Needle-free dual GIP/GLP-1 taken under the tongue — full-dose appetite and body-composition support.
Get started Lower-dose needle-free dual-action therapy under the tongue — a gentle entry point, no injections.
Get started Dual GIP/GLP-1 therapy in a glycine-based formulation — appetite control, insulin sensitivity, and body composition. Standard injection.
Get started Lower-dose dual-action GLP-1/GIP therapy in a glycine-based formulation — gradual, tolerable progress.
Get started GLP-1 therapy supporting appetite regulation, metabolic health, and sustainable body composition. Standard injection.
Get started Lower-dose GLP-1 therapy optimized for longevity, metabolic health, and gradual body-composition support.
Get started Needle-free GLP-1 taken under the tongue — full-dose appetite regulation and steady weight loss, no injections.
Get started Lower-dose needle-free GLP-1 under the tongue — a gentle, gradual entry point with no injections.
Get started GLP-1 therapy in a glycine-based formulation supporting appetite regulation and steady body composition. Standard injection.
Get started Lower-dose GLP-1 therapy in a glycine-based formulation — optimized for longevity and gradual body-composition support.
Get startedHow It Works
Have questions? Book a free consultation. Already know what you want? Order online and complete a short medical intake. Either way takes minutes.
A licensed physician reviews your intake and history — the good-faith exam — to decide whether your therapy is appropriate. They may reach out for a quick conversation first.
If approved, your prescription is compounded by a licensed US pharmacy and shipped discreetly to your door. Your card is only charged once a physician approves.
Follow-up and lab monitoring as needed — with optional full coaching whenever you want a hands-on partner.
Not sure which is right?
A quick consultation helps match the right GLP-1, dose, and delivery to your goals.
Book a free consultation