GLP-1 Weight Loss

Real weight loss, without the markup.

GLP-1 medications — semaglutide and tirzepatide — are among the most rigorously studied weight-loss therapies in modern medicine. Thesis Health makes them accessible — physician-supervised and compounded by licensed US pharmacies through our clinical partner, Lyv Health, at a fraction of brand-name pricing. The same active ingredients as Ozempic® and Mounjaro®* — now including needle-free sublingual options.

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GLP-1 Plans

Simple, honest pricing.

Tirzepatide and semaglutide — as a standard injection or a needle-free sublingual. Pick microdose or full dose on any plan.

A fraction of name-brand — same active ingredient.

Brand-name GLP-1s can run well over $1,000 a month. Thesis starts at $199/mo — roughly $7 a day, about the cost of a coffee — for the same active ingredients* as Ozempic® and Mounjaro®.

*Compounded medications contain the same active ingredient as the brand-name drug but are not FDA-approved finished products. Prescribed and dispensed through our clinical partner, Lyv Health.

Tirzepatide Sublingual

Needle-free · under the tongue

  • Physician-reviewed intake
  • Prescription shipped to your door
  • Needle-free — no injections
  • Same active ingredient as Mounjaro*
  • Dual GIP + GLP-1 mechanism

Semaglutide

Standard injection

  • Physician-reviewed intake
  • Prescription shipped to your door
  • Same active ingredient as Ozempic*
  • Full therapeutic dosing range
  • HSA / FSA eligible

Semaglutide Sublingual

Needle-free · under the tongue

  • Physician-reviewed intake
  • Prescription shipped to your door
  • Needle-free — no injections
  • Same active ingredient as Ozempic*
  • HSA / FSA eligible

Physician evaluation required. *Compounded medications contain the same active ingredient but are not FDA-approved finished drug products. HSA/FSA eligibility varies by plan. Not available in all states. Individual results vary.

The Clinical Evidence

The research is hard to ignore.

GLP-1 medications aren't hype — they're among the most rigorously studied weight-loss therapies in modern medicine. Two landmark, peer-reviewed trials set the benchmark:

~15%

Semaglutide — the STEP 1 trial

Adults lost an average of ~15% of their body weight over 68 weeks. New England Journal of Medicine, 2021

~21%

Tirzepatide — the SURMOUNT-1 trial

At the highest dose, the average was ~21% of body weight over 72 weeks — the most of any GLP-1 to date. New England Journal of Medicine, 2022

See Your Potential

Slide to your weight today

220 lbs
130400 lbs
Semaglutide over ~68 weeks
−33 lbs 187 lbs
Tirzepatide over ~72 weeks
−46 lbs 174 lbs

Projected from the average results of the STEP 1 and SURMOUNT-1 trials. Individual results vary — this is an illustration, not a guarantee or medical advice.

New to GLP-1s?

Learn to do it the right way — free.

Our free GLP-1 course covers how these medications actually work, protecting your lean mass, and keeping the results. No cost, no catch.

Start the free course
Before You Start GLP-1s — the free Thesis Health course The Right Way or No Way — start here 13 min · Free

All Formulations

Every dose & delivery.

Injection or sublingual, microdose or full dose — filter to the option that fits you.

Tirzepatide with B12 — Thesis Health

Tirzepatide with B12

Dual-action GLP-1/GIP therapy — appetite control, insulin sensitivity, and body composition. Standard injection.

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Tirzepatide Microdose with B12 — Thesis Health

Tirzepatide Microdose with B12

Lower-dose dual-action therapy — gradual, tolerable progress with minimal side effects.

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Tirzepatide Sublingual — Thesis Health

Tirzepatide Sublingual

Needle-free dual GIP/GLP-1 taken under the tongue — full-dose appetite and body-composition support.

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Tirzepatide Sublingual Microdose — Thesis Health

Tirzepatide Sublingual Microdose

Lower-dose needle-free dual-action therapy under the tongue — a gentle entry point, no injections.

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Semaglutide with B12 — Thesis Health

Semaglutide with B12

GLP-1 therapy supporting appetite regulation, metabolic health, and sustainable body composition. Standard injection.

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Semaglutide Microdose with B12 — Thesis Health

Semaglutide Microdose with B12

Lower-dose GLP-1 therapy optimized for longevity, metabolic health, and gradual body-composition support.

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Semaglutide Sublingual — Thesis Health

Semaglutide Sublingual

Needle-free GLP-1 taken under the tongue — full-dose appetite regulation and steady weight loss, no injections.

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Semaglutide Sublingual Microdose — Thesis Health

Semaglutide Sublingual Microdose

Lower-dose needle-free GLP-1 under the tongue — a gentle, gradual entry point with no injections.

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How It Works

Simple process. Serious care.

01

Choose your path

Have questions? Book a free consultation. Already know what you want? Order online and complete a short medical intake. Either way takes minutes.

02

Physician review

A licensed physician reviews your intake and history — the good-faith exam — to decide whether your therapy is appropriate. They may reach out for a quick conversation first.

03

Approved, compounded & shipped

If approved, your prescription is compounded by a licensed US pharmacy and shipped discreetly to your door. Your card is only charged once a physician approves.

04

Ongoing support

Follow-up and lab monitoring as needed — with optional full coaching whenever you want a hands-on partner.

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Not sure which is right?

Talk it through — free.

A quick consultation helps match the right GLP-1, dose, and delivery to your goals.

Book a free consultation